As for the actual subject at hand, obviously Novak is the favorite. I think Andy has a better chance of beating Novak than just about anyone else, with the possible exception of Wawrinka. But the problem is, unlike Stan (or even Federer), it isn't really up to Andy - all he can do is play his absolute best and hope that Novak channels his less-consistent 2012-14 self. In other words, Novak surpasses Andy in just about every way, so needs to play well below his level to lose.
To put another way...
Novak plays his A game, and Andy can't win.
Novak plays his B game, and we've got an interesting match if Andy plays his absolute best.
Novak plays his C game...wait, we haven't seen that since 2014, and then only rarely.
Part of what makes Novak so great right now is he doesn't have a C game. His worst is a B game, which is good enough to beat anyone - or rather, everyone except for Roger, Stan, and Andy, and only those three if they play out of their minds (A game). And part of this is because he has masterfully figured out how to peak in tournaments at the right time, like runners who save their best for the last lap.
Now some seem to hope or fear that Novak's play vs. Simon points to the return of Novak's C game. But I'm not ready to say that; we need to see it happen more than one match.